[1]张洪辉,章新琼,丁金霞,等.胃肠道肿瘤患者并发恶性肠梗阻的危险因素分析[J].军事护理,2022,39(10):1-4.[doi:10.3969/j.issn.2097-1826.2022.10.001]
　ZHANG Honghui,ZHANG Xinqiong,DING Jinxia,et al.Risk Factors of Malignant Bowel Obstruction in Patients with Gastrointestinal Tumor[J].Nursing Journal Of Chinese People's Laberation Army,2022,39(10):1-4.[doi:10.3969/j.issn.2097-1826.2022.10.001]
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胃肠道肿瘤患者并发恶性肠梗阻的危险因素分析
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《军事护理》[ISSN:2097-1826/CN:31-3186/R]

卷:
39
期数:
2022年10期
页码:
1-4
栏目:
肿瘤康复护理研究专栏
出版日期:
2022-10-15

文章信息/Info

Title:
Risk Factors of Malignant Bowel Obstruction in Patients with Gastrointestinal Tumor
文章编号:
2097-1826(2022)10-0001-04
作者:
张洪辉1; 章新琼1; 丁金霞2; 汪锦芳2; 刘雪利1
(1.安徽医科大学 护理学院,安徽 合肥230032; 2.安徽医科大学第一附属医院 肿瘤内科,安徽 合肥230022)
Author(s):
ZHANG Honghui1; ZHANG Xinqiong1; DING Jinxia2; WANG Jinfang2; LIU Xueli1
(1.School of Nursing,Anhui Medical University,Hefei 230032,Anhui Province,China; 2.Department of Oncology,The First Affiliated Hospital of Anhui Medical University,Hefei 230022,Anhui Province,China)
关键词:
恶性肠梗阻;  胃肠道肿瘤;  危险因素
Keywords:
malignant bowel obstruction;  gastrointestinal tumor;  risk factors
分类号:
R473.73
DOI:
10.3969/j.issn.2097-1826.2022.10.001
文献标志码:
A
摘要:
目的 评估胃肠道肿瘤患者并发恶性肠梗阻的危险因素,以期为早期识别恶性肠梗阻提供依据。方法 将2019年6月至2021年6月在某三级甲等医院肿瘤内科接受治疗的胃肠道肿瘤并发恶性肠梗阻的78例患者作为暴露组,随机抽取同一时期未发生恶性肠梗阻的胃肠道肿瘤220例患者作为对照组。通过医院电子病历系统收集数据,以Lasso 回归筛选出可能的危险因素,并将其纳入多因素Logistic回归分析。结果 两组在体质量指数、术后时间等24个因素上的差异均有统计学意义(均P<0.05)。恶心呕吐(OR=4.25)、肠梗阻病史(OR=4.48)、腹腔积液(OR=8.00)、便秘(OR=5.52)、低蛋白血症(OR=13.25)、低钾血症(OR=5.62)、高血糖(OR=4.56)是恶性肠梗阻发病的独立危险因素(均P<0.05)。结论 医护人员应关注有肠梗阻病史且伴有恶心呕吐、腹腔积液、便秘、低蛋白血症、低钾血症、高血糖等症状的胃肠道肿瘤患者,并采取针对性措施,以避免恶性肠梗阻的发生。
Abstract:
Objective To evaluate the risk factors of malignant bowel obstruction in patients with gastrointestinal tumor,and to provide evidence for early identification of malignant bowel obstruction. Methods A total of 78 patients with gastrointestinal tumors complicated with malignant intestinal obstruction who were treated in the Medical Oncology Department of a tertiary A hospital from June 2019 to June 2021 were selected as the exposure group,and 220 patients with gastrointestinal tumors without malignant intestinal obstruction during the same period were randomly selected as the control group.Data were collected through the hospital's electronic information medical record system.The possible influencing factors were screened out through lasso regressionand the selected variables were included in the multivariate logistic regression analysis.Results There were significant differences in body mass index,postoperative time and other 24 factors between the two groups(all P<0.05).Nausea and vomiting(OR=4.25),history of intestinal obstruction(OR=4.48),abdominal effusion(OR=8.00),constipation(OR=5.52),hypoproteinemia(OR=13.25),hypokalemia(OR=5.62),hyperglycemia(OR=4.56)were independent risk factors for malignant intestinal obstruction(all P<0.05).Conclusions Attention should be paid to patients with gastrointestinal tumors with a history of intestinal obstruction,accompanied by nausea and vomiting,abdominal effusion,constipation,hypoproteinemia,hypokalemia,hyperglycemia and other symptoms.It is necessary to take targeted measures to avoid the occurrence of malignant intestinal obstruction.

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备注/Memo

备注/Memo:
【 收稿日期 】 2021-10-21 【 修回日期 】 2022-06-08
【 基金项目 】 国家科技部重点研发计划重点专项子课题(2020 YFC2008802); 安徽医科大学青苗培育计划(hlqm2021004)
【 作者简介 】 张洪辉,硕士在读,从事慢性病管理的研究
【 通信作者 】 章新琼,电话:0551-63869181
更新日期/Last Update: 2022-10-15