[1]王晓庆,王宇,于凯,等.精神分裂症患者积极度的潜在类别与药物依从性的关系[J].军事护理,2022,39(10):44-48.[doi:10.3969/j.issn.2097-1826.2022.10.012]
　WANG Xiaoqing,WANG Yu,YU Kai,et al.Relationship Between the Latent Categories of Positivity and Medication Adherence in Patients with Schizophrenia[J].Nursing Journal Of Chinese People's Laberation Army,2022,39(10):44-48.[doi:10.3969/j.issn.2097-1826.2022.10.012]
点击复制

精神分裂症患者积极度的潜在类别与药物依从性的关系
分享到：

《军事护理》[ISSN:2097-1826/CN:31-3186/R]

卷:
39
期数:
2022年10期
页码:
44-48
栏目:
研究荟萃
出版日期:
2022-10-15

文章信息/Info

Title:
Relationship Between the Latent Categories of Positivity and Medication Adherence in Patients with Schizophrenia
文章编号:
2097-1826(2022)10-0044-05
作者:
王晓庆1; 王宇2; 于凯1; 朱婉1; 周郁秋1
(1.哈尔滨医科大学 护理学院,黑龙江 哈尔滨 150081; 2.阜外华中心血管病医院 心脏重症监护病房,河南 郑州 451464)
Author(s):
WANG Xiaoqing1; WANG Yu2; YU Kai1; ZHU Wan1; ZHOU Yuqiu1
(1.School of Nursing,Harbin Medical University,Harbin 150081,Heilongjiang Province,China; 2.Cardiac Intensive Care Unit,Fuwai Central China Cardiovascular Hospital,Zhengzhou 451464,Henan Province,China)
关键词:
精神分裂症;  积极度;  药物依从性;  潜在类别
Keywords:
schizophrenia;  positivity;  medication adherence;  latent category
分类号:
R473.74
DOI:
10.3969/j.issn.2097-1826.2022.10.012
文献标志码:
A
摘要:
目的 探讨精神分裂症患者积极度的潜在类别及药物依从性上的差异,为制订针对性干预方案提供实证依据。方法 2021年12月至 2022年4月,采用方便抽样法选取黑龙江省某精神专科医院的门诊患者220名为研究对象,采用患者积极度量表(patient activation measure,PAM)和药物依从性量表(medication adherence rating scale,MARS)进行调查。对精神分裂症患者的积极度特征进行潜在剖面分析,并通过单因素分析、二元Logistic回归比较不同类别患者在人口学变量和药物依从性上的差异。结果 精神分裂症患者积极度类别分为被动依从型(52.7%)和相对自主型(47.3%)2类。不同积极度类别的精神分裂症患者在年龄、户口类型、文化程度、职业状态、家庭人均月收入、药物不良反应、病程、初始治疗延迟时间、复发次数、MARS得分上的差异均有统计学意义(均P<0.05)。文化程度、初始治疗延迟时间、复发次数及MARS得分是精神分裂症患者积极度潜在类别的独立预测因子(均P<0.05)。结论 精神分裂症患者的积极度存在2种潜在类别,应依据不同类别患者的特征制定针对性干预策略,并在提高积极度、改善药物依从性方面给予被动依从型患者更多关注。
Abstract:
Objective To explore the potential categories of positivity and medication adherence in patients with schizophrenia,and to provide a basis for targeted intervention plans in clinical settings.Methods From December 2021 to April 2022,220 outpatients from a psychiatric hospital in Heilongjiang province were selected by the convenience sampling method.A questionnaire survey was conducted with patient activation measure(PAM)and medication adherence rating scale(MARS).The characteristics of positivity in schizophrenia patients were analyzed by potential profile analysis,and the differences in demographic variables and medication compliance among different categories of patients were compared by univariate analysis and binary Logistic regression.Results The analysis showed that 2 latent categories emerged,namely,passive compliance group(52.7%)and relative autonomy group(47.3%).Different types of patients had significant differences in age,household,education level,occupation status,family per capita monthly income,drug side effects,course of disease,delay time of initial treatment,recurrence times,and MARS score(all P<0.05).Conclusions There are two latent categories of positive degree in patients with schizophrenia.Targeted intervention strategies should be formulated according to the characteristics of different categories of patients,and more attention should be paid to patients with passive compliance in improving positive degree and drug compliance.

参考文献/References:

[1] VALAPARLA V L,NEHRA R,MEHTA U M,et al.Social cognition of patients with schizophrenia across the phases of illness—a longitudinal study[J].Schizophr Res,2017(190):150-159.
[2] YU W,TONG J,SUN X,et al.Analysis of medication adherence and its influencing factors in patients with schizophrenia in the Chinese institutional environment[J/OL].[2022-05-01].https://www.mdpi.com/1660-4601/18/9/4746 DOI:10.3390/ijerph18094746.
[3] JIN H,MOSWEU I.The societal cost of schizophrenia:a systematic review[J].Pharmacoeconomics,2017,35(1):25-42.
[4] 杨安文,徐东,代伯峰,等.药片计数法在精神分裂症患者服药依从性测量中的应用[J].解放军护理杂志,2018,35(3):46-50.
[5] HADDAD P M,BRAIN C,SCOTT J.Nonadherence with antipsychotic medication in schizophrenia:challenges and management strategies[J].Patient Relat Outcome Meas,2014(5):43-62.
[6] HIBBARD J H,MAHONEY E R,STOCKARD J,et al.Development and testing of a short form of the patient activation measure[J].Health Serv Res,2005,40(6 Pt 1):1918-1930.
[7] CHIANG Y S,CHANG Y C,LIU Y P,et al.Quality of life in patients with comorbid serious mental illness and chronic diseases:a structural equation model[J].J Adv Nurs,2021,77(3):1271-1283.
[8] LIM K,SMUCNY J,BARCH D M,et al.Cognitive subtyping in Schizophrenia:a latent profile analysis[J].Schizophrenia Bull,2021,47(3):712-721.
[9] 美国精神医学学会.精神障碍诊断与统计手册[M].张道龙,译.北京:北京大学出版社,2016:114.
[10]ZHANG Q,LI X,PARKER G J,et al.Theory of mind correlates with clinical insight but not cognitive insight in patients with schizophrenia[J].Psychiatry Res,2016(237):188-195.
[11]洪洋,邹叶芳,吴娟.中文版患者积极度量表的信效度研究[J].中华现代护理杂志,2018,24(25):3009-3015.
[12]KAO Y C,LIU Y P.Compliance and schizophrenia:the predictive potential of insight into illness,symptoms,and side effects[J].Compr Psychiatry,2010,51(6):557-565.
[13]FIALKO L,GARETY P A,KUIPERS E,et al.A large-scale validation study of the medication adherence rating scale(MARS)[J].Schizophr Res,2008,100(1-3):53-59.
[14]LUBKE G,MUTHEN B.Performance of factor mixture models as a function of model size,covariate effects,and class-specific parameters[J].Struct Equ Modeling,2007,14(1):26-47.
[15]STEIN-PARBURY J,GALLAGHER R,CHENOWETH L,et al.Factors associated with good self-management in older adults with a schizophrenic disorder compared with older adults with physical illnesses[J].J Psychiatr Ment Health Nurs,2012,19(2):146-153.
[16]翁永振.精神分裂症的康复操作手册[M].北京:人民卫生出版社,2009:175-232.
[17]MARESOVA P,JAVANMARDI E,BARAKOVIC S,et al.Consequences of chronic diseases and other limitations associated with old age—a scoping review[J/OL].[2022-05-01].https://bmcpublichealth.biomedcentral.com/articles/10.1186/s12889-019-7762-5.DOI:10.1186/s12889-019-7762-5.
[18]SIN N L,LYUBOMIRSKY S.Enhancing well-being and alleviating depressive symptoms with positive psychology interventions:a practice-friendly meta-analysis[J].J clin psychol,2009,65(5):467-487.
[19]LUBETKIN E I,LU W H,GOLD M R.Levels and correlates of patient activation in health center settings:building strategies for improving health outcomes[J].J Health Care Poor Underserved,2010,21(3):796-808.
[20]RAN M,XIANG M,HUANG M,et al.Natural course of schizophrenia:2-year follow-up study in a rural Chinese community[J].Br J Psychiatry,2001(178):154-158.
[21]康晓凤.慢性心力衰竭患者亚群模型及自我管理支持策略研究[D].北京:北京协和医学院·中国医学科学院,2012.
[22]屈金莲,张涛,宋杰,等.出院后精神分裂症患者服药依从性电话和短信干预的1年随访[J].中国心理卫生杂志,2015,29(9):656-661.
[23]樊惠颖,邹海欧,张冲,等.精神分裂症患者自我管理类型的研究[J].中华护理杂志,2014,49(12):1467-1470.
[24]COULTER A,ENTWISTLE V A,ECCLES A,et al.Personalised care planning for adults with chronic or long-term health conditions[J/OL].[2022-05-01].https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD010523.pub2/full.DOI:10.1002/14651858.CD010523.pub2.

相似文献/References:

[1]王宇,李英丽,周郁秋.稳定期精神分裂症患者社区融合体验的质性研究[J].军事护理,2021,38(04):25.[doi:10.3969/j.issn.1008-9993.2021.04.007]
　WANF Yu,LI Yingli,ZHOU Yuqiu.Community Integration Experience of Patients with Schizophrenia in Stable Period: A Qualitative Study[J].Nursing Journal Of Chinese People's Laberation Army,2021,38(10):25.[doi:10.3969/j.issn.1008-9993.2021.04.007]
[2]宋锦,于凯,马锐,等.精神分裂症诊治延误患者就医体验的质性研究[J].军事护理,2023,40(11):70.[doi:10.3969/j.issn.2097-1826.2023.11.017]
　SONG Jin,YU Kai,MA Rui,et al.Medical Experience of Patients with Delayed Diagnosis and Treatment of Schizophrenia: A Qualitative Study[J].Nursing Journal Of Chinese People's Laberation Army,2023,40(10):70.[doi:10.3969/j.issn.2097-1826.2023.11.017]

备注/Memo

备注/Memo:
【 收稿日期 】 2022-06-07 【 修回日期 】 2022-09-11
【 基金项目 】 国家自然科学基金项目(72074063); 大庆市指导性科技计划项目(zdy-2021-86)
【 作者简介 】 王晓庆,硕士在读,从事精神心理卫生研究
【 通信作者 】 周郁秋,电话:0459-8153066
更新日期/Last Update: 2022-10-15